Published in 1951, The Catcher in the Rye has become a common part of high school and college curricula throughout the English-speaking world and has been translated into all major languages. Since its publication, it has reportedly sold more than 65 million copies. The novel's antihero, Holden Caulfield, has become a cultural icon for teenage rebellion. Due to its liberal use of profanity and portrayal of sexuality and teenage angst, it has frequently been met with censorship challenges in the United States making it one of the most challenged books of the 20th century.

Holden Caulfield, a depressed 17-year-old, lives in a sanitorium in California after the end of World War II. After his discharge within a month, he intends to go live with his brother D.B., an author and war veteran with whom Holden is angry for becoming a Hollywood screenwriter.

Holden recalls the events of a single night during the previous year's Christmas, beginning at Pencey Preparatory Academy, a boarding school in Pennsylvania that Salinger may have based on the Valley Forge Military Academy and College.[13] Holden has just been expelled from Pencey because he had failed all of his classes except English. After causing the fencing team to forfeit a fencing match in New York because he accidentally lost the team’s equipment on the subway, he says goodbye to his history teacher, Mr. Spencer, who is a well-meaning but long-winded old man. Spencer offers him advice and simultaneously embarrasses Holden by criticizing his history exam.

Back at his dorm, Holden's dorm neighbor, Robert Ackley, who is unpopular among his peers, disturbs Holden with his impolite questioning and mannerisms. Holden, who feels sorry for Ackley, tolerates his presence. Later, Holden agrees to write an English composition for his roommate, Ward Stradlater, who is leaving for a date. Holden and Stradlater normally hang out well together, and Holden admires Stradlater's physique. He is distressed to learn that Stradlater's date is Jane Gallagher, with whom Holden was infatuated, and whom he feels the need to protect. That night, Holden decides to go to a Cary Grant comedy with Mal Brossard and Ackley. Since Ackley and Mal had already seen the film, they end up just eating food and playing pinball for a while and returning to Pencey. When Stradlater returns hours later, he fails to appreciate the deeply personal composition Holden wrote for him about the baseball glove of Holden's late brother Allie who died from leukemia a few years prior, and refuses to say whether he had sex with Jane. Enraged, Holden punches him, and Stradlater easily wins the fight. When Holden continues insulting him, Stradlater leaves him lying on the floor with a bloody nose. Fed up with the "phonies" at Pencey Prep, Holden decides to leave Pencey early and catches a train to New York. Holden intends to stay away from his home until Wednesday when his parents would have received notification of his expulsion. Aboard the train, Holden meets the mother of a wealthy, obnoxious Pencey student, Ernest Morrow, and makes up nice but false stories about her son.